Article No
155-32-230
Specifications
| NCBI Number | 6347 |
| Accession Number | P13500 |
| Application | ELISA, WB |
| Article No | 155-32-230 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1A7B8 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | MCP-1 Antibody [1A7B8] |
| Supplier | ProSci |
| Entrez Gene ID | 6347 |
| Gene Symbol | CCL2 |
| Immunogen | Ni-NTA purified recombinant human MCP-1 expressed in E.Coli strain BL21 (DE3). |
| Isotype | IgG1 k |
| Notes | Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH. |
| Alias Names | MCP1, SCYA2, HC11, MCAF, MCP1, MCP-1, GDCF-2, SMC-CF, HSMCR30 |
| Previous Article No | 155-32-230-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Western Blot:1:500 - 1,000 ELISA:1,000 - 2,000. |
| Purification | Protein A Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | to MCP-1 monoclonal antibody can be stored at -20°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Substrate / Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
| UniProt Number | P13500 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
