Article No
155-20-274
Antibodies Primary
SARS-CoV-2 (COVID-19) Envelope
SARS-CoV-2 (COVID-19) Envelope Antibody
Suggested protocols
Specifications
| MW | 53 kDa |
| NCBI Number | 43740570 |
| Application | WB |
| Article No | 155-20-274 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU |
| Clone Type | polyclonal |
| Concentration | batch dependent |
| Conjugation | Unconjugated |
| Description | SARS-CoV-2 (COVID-19) Envelope Antibody |
| Supplier | ProSci |
| Entrez Gene ID | 43740570 |
| Format | Liquid |
| Gene Symbol | E |
| Immunogen | GST-SARS-CoV2 E Protein |
| Notes | Coronavirus envelope (E) proteins are short (1 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction. |
| Alias Names | SARS-CoV-2-E Protein, SARS-CoV-2-Envelope Protein |
| Product Type | Antibodies Primary |
| Protocol | Detection Antibodies: 1 µg/ml Ab, 5% BSA in TBS-T, 4C overnight Blocking: 5% milk in TBS-T, 1h room temp Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-mouse, in TBS-T, 1h room temp Wash: TBS-T, 4x 10 min |
| Purification | Affinity Purified |
| Shipping Information | DRY ICE |
| Size | 0.1 mg |
| Source / Host | sheep/ovine |
| Species Reactivity | virus |
| Storage | Aliquot and store at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Substrate / Buffer | Antibody supplied in PBS. |
| Swiss-Prot No | P0DTC4 |
| Product Page Updated | 2022-01-19T14:40:48.336Z |
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