Antibodies Primary

SARS-CoV-2 (COVID-19) Envelope

SARS-CoV-2 (COVID-19) Envelope Antibody

Article No

155-20-274

Application

WB

Species Reactivity

virus

Size

0.1 mg

Source / Host

sheep/ovine

Shipping Information

DRY ICE

Suggested protocols

Specifications

MW 53 kDa
NCBI Number 43740570
Application WB
Article No 155-20-274
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL, RU
Clone Type polyclonal
Concentration batch dependent
Conjugation Unconjugated
Description SARS-CoV-2 (COVID-19) Envelope Antibody
Supplier ProSci
Entrez Gene ID 43740570
Format Liquid
Gene Symbol E
Immunogen GST-SARS-CoV2 E Protein
Notes Coronavirus envelope (E) proteins are short (1 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Alias Names SARS-CoV-2-E Protein, SARS-CoV-2-Envelope Protein
Product Type Antibodies Primary
Protocol Detection Antibodies: 1 µg/ml Ab, 5% BSA in TBS-T, 4C overnight Blocking: 5% milk in TBS-T, 1h room temp Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-mouse, in TBS-T, 1h room temp Wash: TBS-T, 4x 10 min
Purification Affinity Purified
Shipping Information DRY ICE
Size 0.1 mg
Source / Host sheep/ovine
Species Reactivity virus
Storage Aliquot and store at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Substrate / Buffer Antibody supplied in PBS.
Swiss-Prot No P0DTC4
Product Page Updated 2022-01-19T14:40:48.336Z

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