Article No
155-10-406
MW | 22.03kDa |
Accession Number | QHD43415.1 |
Article No | 155-10-406 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Description | SARS-CoV-2 (COVID-19) NSP3 Recombinant Protein |
Supplier | ProSci |
Format | Lyophilized |
Notes | The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells. |
Alias Names | nsp3,PL-PRO,Papain-like proteinase,X domain(Macro domain) |
Previous Article No | 155-10-406-0.1 |
Product Type | Proteins & Peptides |
Protocol | Immunogen |
Purity | >90% |
Shipping Information | RT |
Size | 0.1 mg |
Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. |
Substrate / Buffer | Supplied as lyophilized from PBS, pH7.5 |
Product Page Updated | 2024-01-03T13:34:25.701Z |