Article No
154-21498
CAS No | 28656-91-9 |
Additional Information | A sea sponge metabolite with diverse biological activities; induces cell death in MCF-7 and ZR-75-1 human breast cancer cells in a time- and concentration-dependent manner from 0.25-0.5 μM; blocks EGF-induced endocytosis of EGFR and EGF-dependent cell proliferation in MCF-7 cells; inhibits BAE cell proliferation and cord formation in a Matrigel™ assay; inhibits angiogenesis in a CAM assay from 1.5-3 nmol per egg; has antibacterial activity against Gram-positive bacteria; inhibits HIV-1 replication (IC50 = 14.6 μM) |
Article No | 154-21498 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO |
Description | (+)-Aeroplysinin-1 |
Supplier | Cayman Chemical |
Format | A solid |
Keywords | Small Molecule Inhibitors |
Notes | A sea sponge metabolite with diverse biological activities; induces cell death in MCF-7 and ZR-75-1 human breast cancer cells in a time- and concentration-dependent manner from 0.25-0.5 μM; blocks EGF-induced endocytosis of EGFR and EGF-dependent cell proliferation in MCF-7 cells; inhibits BAE cell proliferation and cord formation in a Matrigel™ assay; inhibits angiogenesis in a CAM assay from 1.5-3 nmol per egg; has antibacterial activity against Gram-positive bacteria; inhibits HIV-1 replication (IC50 = 14.6 μM) |
Alias Names | NSC 170364 |
Product Type | Chemicals & Biochemicals |
Purity | ≥95% |
Shipping Information | -20 |
Size | 100 µg |
Storage | -20 |
Substrate / Buffer | A solid |
Product Page Updated | 2023-01-13T16:08:44.036Z |