Article No
154-14007-1
Specifications
| CAS No | 38966-21-1 |
| Additional Information | A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels. |
| Article No | 154-14007-1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, RU |
| Description | (+)-Aphidicolin |
| Supplier | Cayman Chemical |
| Format | A solid |
| Notes | (+)-Aphidicolin is a natural tetracyclic diterpene first isolated from the fungus C. aphidicola and shown to have antiviral activity against herpes simplex.{22496} In eukaryotic cells, it is a cell-permeable, reversible inhibitor of DNA replication, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.{22501,22499,22497} Aphidicolin can be used, at 3 μM, to arrest cells in G1/S phase or to increase gene amplification frequency.{22498,22502} |
| Alias Names | ICI 69653|NSC 234714 |
| Product Type | Chemicals & Biochemicals |
| Purity | ≥98% |
| Shipping Information | -20 |
| Size | 1 mg |
| Storage | -20 |
| Substrate / Buffer | A solid |
| Product Page Updated | 2022-01-10T15:00:37.033Z |
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