Article No
12-1242-20
Smooth Muscle Myosin Heavy Chain (SM-MHC)
Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) Recombinant Rabbit Monoclonal Antibody (Clone:MYH11/2303R)
Antibodies Primary
Specifications
| Application | IHC |
| Article No | 12-1242-20 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MYH11/2303R |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) Recombinant Rabbit Monoclonal Antibody (Clone:MYH11/2303R) |
| Supplier | Abeomics |
| Entrez Gene ID | 4629 |
| Gene Symbol | MYH11 |
| Immunogen | Human full-length recombinant MYH11 protein |
| Isotype | IgG |
| Notes | Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors. |
| Alias Names | AAT4; Myosin heavy chain 11 (MYH11); Myosin heavy chain 11 smooth muscle; Smooth muscle myosin heavy chain 11; Myosin-11; SM1; SM2; SMHC; SMMHC |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Protein A/G Purified |
| Shipping Information | Blue Ice |
| Size | 20 µg |
| Source / Host | rabbit |
| Species Reactivity | human, rat |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P35749 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
