Article No
12-1188-100
HCG-beta (Pregnancy & Choriocarcinoma Marker)
Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:HCGb/1985R)
Antibodies Primary
Specifications
| Application | IHC |
| Article No | 12-1188-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | HCGb/1985R |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:HCGb/1985R) |
| Supplier | Abeomics |
| Entrez Gene ID | 1082,93659,94027,94115 |
| Gene Symbol | CGB3, CGB5, CGB7, CGB8 |
| Immunogen | Recombinant full-length hCG beta protein |
| Isotype | IgG |
| Notes | This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains. The hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. |
| Alias Names | CG-beta; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin Subunit beta; hCGB |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (Formalin-fixed) (1-2µg/ml; 30 min RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Protein A/G Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P01233 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
