Article No
12-1018-100
Chromogranin A / CHGA (Neuroendocrine Marker)
Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1815R)
Antibodies Primary
Specifications
| Application | IHC |
| Article No | 12-1018-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | CHGA/1815R |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1815R) |
| Supplier | Abeomics |
| Entrez Gene ID | 1113 |
| Gene Symbol | CHGA |
| Immunogen | Recombinant full-length human CHGA protein |
| Isotype | IgG |
| Keywords | Recombinant rabbit antibodies, Chromogranin A / CHGA (Neuroendocrine Marker), CHGA, 1113, P10645, Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Pituitary Secretory Protein I, SP-I, Vasostatin I or II, CHGA/1815R, Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1815R), Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker) |
| Notes | Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin. |
| Alias Names | Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Pituitary Secretory Protein I, SP-I, Vasostatin I or II |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 200 µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P10645 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
