Article No
11-7010-100
Histone H2A.x
Polyclonal Antibody to Histone H2A.x
Antibodies Primary
Specifications
| Application | WB |
| Article No | 11-7010-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Polyclonal Antibody to Histone H2A.x |
| Supplier | Abeomics |
| Entrez Gene ID | 3014 |
| Gene Symbol | H2AX |
| Immunogen | Full length recombinant Histone H2A.x protein was used as the immunogen for this antibody. |
| Isotype | IgG |
| Notes | Histones are major chromatin proteins that wrap DNA to form nucleosome particles. Each nucleosome core particle consists of approximately 146 bp DNA wrapped by an octamer containing 2 molecules each of histones H2A, H2B, H3, and H4. Histone H1 sits on the linker DNA between nucleosomes. Their major function is to compact long DNA strands inside the nucleus and chromatin regulation. Histone H2A X is a 15 kDa variant of Histone H2. Histone H2A X is also required for the repair of double-stranded DNA breaks particularly when modified by C-terminal phosphorylation on Ser-140. Histone H2A X is expressed in all eukaryotic cells. |
| Alias Names | H2AFX||H2AX |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml |
| Purification | Protein A Purified |
| Research area | Epigenetics |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store the antibody at 4⁰C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing |
| Substrate / Buffer | 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P16104 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
