Article No
11-1017-25
14-3-3 Zeta
Polyclonal Antibody to 14-3-3 Zeta
Antibodies Primary
Specifications
| Application | WB |
| Article No | 11-1017-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Polyclonal Antibody to 14-3-3 Zeta |
| Supplier | Abeomics |
| Entrez Gene ID | 7534 |
| Gene Symbol | YWHAZ |
| Immunogen | A partial length recombinant 14-3-3 Zeta protein (amino acids 30-245) was used as the immunogen for this antibody. |
| Isotype | IgG |
| Notes | 14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer). |
| Alias Names | YWHAZ |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 1-2 µg/ml |
| Purification | Protein A Purified |
| Research area | Cell Death |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store the antibody at 4⁰C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P63104 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
