Article No
10-7010-25
DNMT2
Monoclonal Antibody to DNMT2 (Clone: ABM1H70)
Antibodies Primary
Specifications
| Application | FC, WB |
| Article No | 10-7010-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM1H70 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to DNMT2 (Clone: ABM1H70) |
| Supplier | Abeomics |
| Entrez Gene ID | 1787 |
| Gene Symbol | TRDMT1 |
| Immunogen | A partial length recombinant protein from DNMT2 was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | DNA methylation and Repair, DNMT2, 1787, Q6ICS7, HCG23994, isoform CRA_a, cDNA FLJ76302, Highly similar to Homo sapiens DNA (cytosine-5-)-methyltransferase 2 (DNMT2), tRNA aspartic acid methyltransferase 1 variant 3, ABM1H70, Monoclonal Antibody to DNMT2(Clone :ABM1H70), Anti DNMT2 Antibody, DNMT2 Antibody |
| Notes | DNMT2, also known as tRNA-aspartic acid methyltransferase 1 (TRDMT1), is highly conserved cytosine-C5 methyltransferase that introduces the C38 methylation of tRNAAsp in many species, including lower eukaryotes, plants, insects, and humans. DNMT2 contains all 10 sequence motifs that are conserved among m5C MTases, including the consensus S-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide. It is a relatively small protein of 391 amino acids and lacks the large N-terminal domains present in the DNMT1 and DNMT3 families. DNMT2 is ubiquitously expressed with multiple mRNA species in most human and mouse adult tissues. It is variably expressed in human cancer cell lines. |
| Alias Names | tRNA (cytosine(38)-C(5))-methyltransferase , DNA (cytosine-5)-methyltransferase-like protein 2, DNA methyltransferase homolog HsaIIP, DNA MTase homolog HsaIIP, M.HsaIIP, PuMet |
| Product Type | Antibodies Primary |
| Protocol | WB: 4-6 µg/ml, FACS: 0.5-1 µg/10^6 |
| Purification | Protein G Purified |
| Research area | Epigenetics |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | O14717 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
