Article No
10-4059-25
TSLP Receptor
Monoclonal Antibody to TSLP Receptor (Clone: ABM2D87)
Antibodies Primary
Specifications
| Application | WB |
| Article No | 10-4059-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM2D87 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to TSLP Receptor (Clone: ABM2D87) |
| Supplier | Abeomics |
| Entrez Gene ID | 64109 |
| Gene Symbol | CRLF2 |
| Immunogen | A partial length recombinant TSLPR protein (amino acids 97-252) was used as the immunogen for this antibody. |
| Isotype | IgG2b k |
| Keywords | Immunology, CRLF2, 64109, Q9HC73, CRLF2, CRL2, ILXR, TSLPR, ABM2D87, Monoclonal Antibody to TSLP Receptor(Clone :ABM2D87), Anti TSLP Receptor Antibody, TSLP Receptor Antibody |
| Notes | TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias). |
| Alias Names | CRLF2||CRL2||ILXR||TSLPR |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml |
| Purification | Protein G Purified |
| Find out more about our research areas Biochemical, Immunology, Molecular Biology and Pathology | Immunology |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | Q9HC73 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
