Article No
10-4049-25
CD161
Monoclonal antibody to CD161 (clone: ABM27F5)
Antibodies Primary
Specifications
| Application | FC |
| Article No | 10-4049-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM27F5 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal antibody to CD161 (clone: ABM27F5) |
| Supplier | Abeomics |
| Entrez Gene ID | 3820 |
| Gene Symbol | KLRB1 |
| Immunogen | Full length recombinant protein of hCD161 was used as the immunogen for this antibody. |
| Isotype | IgG2b k |
| Keywords | Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, HNKR-P1a, NKR-P1A, Natural killer cell surface protein P1A, CD161 |
| Notes | CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin superfamily. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD). |
| Alias Names | Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, HNKR-P1a, NKR-P1A, Natural killer cell surface protein P1A, CD161 |
| Product Type | Antibodies Primary |
| Protocol | FACS analysis: 0.5-1 µg/10^6 cells |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | Q12918 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
