Article No
10-4048-25
CD161
Monoclonal Antibody to CD161 (Clone: ABM2D74)
Antibodies Primary
Specifications
| Application | FC, IHC, WB |
| Article No | 10-4048-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM2D74 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to CD161 (Clone: ABM2D74) |
| Supplier | Abeomics |
| Entrez Gene ID | 3820 |
| Gene Symbol | KLRB1 |
| Immunogen | A full length human CD161 protein was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | Immunology, KLRB1, 3820, Q12918, KLRB1, CLEC5B, NKRP1A, ABM2D74, Monoclonal Antibody to CD161(Clone :ABM2D74), Anti CD161 Antibody, CD161 Antibody |
| Notes | CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin superfamily. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD). |
| Alias Names | KLRB1||CLEC5B||NKRP1A |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml FACS: 0.2-0.5 µg/10^6 cells |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | Q12918 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
