Article No
10-3015-100
TLR7
Monoclonal Antibody to TLR7 (Clone: ABM2C27)
Antibodies Primary
Specifications
| Application | FC, IHC |
| Article No | 10-3015-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM2C27 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to TLR7 (Clone: ABM2C27) |
| Supplier | Abeomics |
| Entrez Gene ID | 51284 |
| Gene Symbol | TLR7 |
| Immunogen | A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | Antibody to TLR7||Anti-TLR7 Antibody||TLR7 Antibody |
| Notes | TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells. |
| Alias Names | TLR7||UNQ248/PRO285 |
| Product Type | Antibodies Primary |
| Protocol | FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | Q9NYK1 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
