Article No
10-3012-F-100
MyD88
Monoclonal antibody to MyD88 (Clone: ABM2H20) FITC Conjugated
Antibodies Primary
Specifications
| Application | FC |
| Article No | 10-3012-F-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM2H20 |
| Clone Type | monoclonal |
| Conjugation | FITC |
| Description | Monoclonal antibody to MyD88 (Clone: ABM2H20) FITC Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 4615 |
| Gene Symbol | MYD88 |
| Immunogen | A partial length recombinant protein of human MyD88 (amino acids 13-221) was used as an immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | Antibody to MyD88||Anti-MyD88 Antibody||MyD88 Antibody |
| Notes | MyD88 (Myeloid differentiation factor) is an essential adaptor molecule in all TLR (Toll-like receptor) signaling pathways except TLR3. MyD88 is composed of an N-terminal (Death Domain) and a highly conserved C-terminal TIR (Toll/interleukin-1 Receptor) domain. It is found to stimulate IL-1R/IL18R-mediated signaling. MyD88-dependent signaling is also important in the regulation of innate as well as acquired immunity, in particular, T-cell responses, to various microbial pathogens. After activation of TLRs, MyD88 is phosphorylated and subsequently recruits IRAKs (IL-1R Associated Kinases) and other downstream proteins such as TRAF6, finally resulting in activation of the NF-kappaB (nuclear factor kappa B) pathway. |
| Product Type | Antibodies Primary |
| Protocol | FACS Analysis: 0.5-1 µg/ml |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. Do not freeze. |
| Substrate / Buffer | 0.2 mg/ ml of Tris buffer containing 0.05% sodium azide. |
| UniProt Number | Q99836 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
