Article No
10-3005-NALE-100
Application | FC, IHC |
Article No | 10-3005-NALE-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | ABM15F6 |
Clone Type | monoclonal |
Description | NALE™ Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6) |
Supplier | Abeomics |
Entrez Gene ID | 51311 |
Gene Symbol | TLR8 |
Immunogen | A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody. |
Isotype | IgG1 k |
Keywords | Antibody to TLR8/CD288||Anti-TLR8/CD288 Antibody||TLR8/CD288 Antibody |
Notes | Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes. |
Alias Names | TLR8||UNQ249/PRO286 |
Product Type | Antibodies Primary |
Protocol | Immunohistochemical analysis: 5 µg/ml;FACS analysis: 2 µg/10^6 cells |
Purification | Protein G Purified |
Research area | Immunology |
Shipping Information | Blue Ice |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Substrate / Buffer | 100 µg in 200 µl PBS containing 0.05% BSA. Azide free, low endotoxin. |
UniProt Number | Q9NR97 |
Product Page Updated | 2024-04-03T14:02:41.041Z |