Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)
Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.
Apoptosis, YWHAQ, 14-3-3 protein tau 14-3-3 protein theta, ABM52H6, Monoclonal Antibody to 14-3-3 Theta(Clone :ABM52H6), Anti 14-3-3 Theta Antibody, 14-3-3 Theta Antibody
14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.
14-3-3 protein tau
WB: 2-4 µg/ml
Protein G Chromatography
Source / Host
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Substrate / Buffer
25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
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The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.