Antibodies Primary

14-3-3 Theta

NEW
Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)

Article No

10-1058-100

Application

WB

Species Reactivity

mouse

Size

100 µg

Clone

ABM52H6

Source / Host

rat

Product insert

Suggested protocols

Specifications

Application WB
Article No 10-1058-100
Clone ABM52H6
Clone Type monoclonal
Conjugation Unconjugated
Description Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)
Supplier Abeomics
Format Purified
Immunogen Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.
Isotype IgG2a
Keywords Apoptosis, YWHAQ, 14-3-3 protein tau 14-3-3 protein theta, ABM52H6, Monoclonal Antibody to 14-3-3 Theta(Clone :ABM52H6), Anti 14-3-3 Theta Antibody, 14-3-3 Theta Antibody
Notes 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.
Alias Names 14-3-3 protein tau
Product Type Antibodies Primary
Protocol WB: 2-4 µg/ml
Purification Protein G Chromatography
Research Area Cell Death
Size 100 µg
Source / Host rat
Species Reactivity mouse
Storage Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Substrate / Buffer 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
UniProt Number P68254
Product Page Updated 2019-04-24T15:22:26.078Z

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