14-3-3 Theta

14-3-3 Theta

Article No 10-1058-100
Product Type Antibodies Primary
Research Area Cell Death
Application WB
Format Purified
Size 100 µg

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Specifications

Country Availability SE, FI, DK, NO, IS, EE, LV, LT
Clone ABM52H6
Clone Type monoclonal
Conjugation Unconjugated
Data Sheet Link https://www.abeomics.com/download_pdf.php?pID=116143
Description Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)
Supplier Abeomics
Immunogen Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.
Isotype IgG2a
Keywords Apoptosis, YWHAQ, 14-3-3 protein tau 14-3-3 protein theta, ABM52H6, Monoclonal Antibody to 14-3-3 Theta(Clone :ABM52H6), Anti 14-3-3 Theta Antibody, 14-3-3 Theta Antibody
Notes 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.
Alias Names 14-3-3 protein tau
Protocol WB: 2-4 µg/ml
Purification Protein G Chromatography
Size 100
Size Unit µg
Source / Host rat
Species Reactivity mouse
Storage Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Substrate / Buffer 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
UniProt Number P68254
Product Page Updated 2019-04-24T15:22:26.078Z

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Source/Host:

rat rat

Species reactivity:

mouse mouse

Product insert:

Product data sheet

Datasheet

Suggested protocols:

Western Blot

Western Blot