T-cell-mediated immunity

Until now, immunity against new coronavirus; SARS-COV-2 was mostly centered around the antibody response. A recent study from Karolinska Institute highlighted the immune response against SARS-COV-2 is not limited to the antibody production. 200 people from blood donors as well as some infected people has been tested for both antibodies and T-cell response against SARS-nCOV-2. Study showed that 30% of the blood donors tested had reactive T-cells against the new coronavirus, even if they had undetectable levels of antibodies.

Although this is great news that immunity against SARS-COV-2 might be higher than we thought we still have a lot to learn.

Whether to see complete picture how immune system reacts to the new coronavirus or to develop a vaccine or therapeutic agents, scientists need reliable and specific tools.

View Nordic BioSite’s excellent selection of tetramers and SARS-COV-2 peptides to track specific T-cells and to monitor vaccine candidates.

Name / Allele Cat #
Flex-T™ HLA-A*01:01 Monomer UVX 280001
Flex-T™ HLA-A*11:01 Monomer UVX 280007
Flex-T™ Biotin HLA-A*02:01 SARS-Cov-2 Monomer (VLNDILSRL) 280029
Custom Biotinylated Monomer – DRB1*01:01 (CP) TBCM6-R1011C-M

 

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Immune Detection Reagents for COVID-19 Research

SPC017 Class I LLLDDFVEII SARS-CoV-2 ORF1ab (6749-6758) Peptide
SPC016 Class I FLLNKEMYL SARS-CoV-2 ORF1ab (3183-3191) Peptide
SPC015 Class I FLAHIQWMV SARS-CoV-2 ORF1ab (3122-3130) Peptide
SPC014 Class II YFTSDYYQLYSTQLS SARS-CoV-2 ORF3a protein (206-220) Peptide
SPC013 Class II WPQIAQFAPSASAFF SARS-CoV-2 nucleocapsid phosphoprotein (301-315) Peptide
SPC012 Class II TRFQTLLALHRSYLT SARS-CoV-2 chain A spike glycoprotein (236-250) Peptide

 

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