Nordic Biosite is proud to announce that our two Optibodies™, Calretinin and Desmin have achieved optimal results in the latest run 64 in the independent quality assessment by NordiQC. Read below to learn more about our Optibodies™ .
The aim of Nordic immunohistochemical Quality Control (NordiQC) is to promote the quality of immunohistochemistry and expand its clinical use by arranging schemes for immunohistochemical proficiency testing and providing examples of recommended protocols tissue controls and other relevant information including descriptions of epitopes and technical protocol parameters.
BSH-4005 Calretinin, Clone BSR235
Calretinin is a calcium-binding protein, and it is expressed in neurons and in nervous system. Calretinin is also expressed in mesothelial cells and steroid producing cells e.g., Leydig cells and adrenal cortical cells as well as fat cells and some neuroendocrine cells. Calretinin located in the cells to nucleus and cytoplasm. Calretinin is useful for mesothelioma diagnostic (differentiate diagnostic between mesothelioma from carcinoma) and it is expressed in most malignant mesothelioma. Calretinin is also applicable for the differential diagnosis of ovarian stromal tumors. Our Calretinin antibody (clone BSR235) has great sensitivity and specificity with excellent signal-to-noise ratio.
BSH-7082 Desmin, Clone BS21
Desmin belongs to the intermediate filament family and is a class III intermediate filament found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts. Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response. Desmin is especially useful for identification of leiomyosarcoma, rhabdomyosarcoma and other myogenic and mesenchymal neoplasms. Our Desmin antibody (clone BS21) offer very sensitive and specific staining pattern with excellent signal-to-noise ratio.
Optibodies™ is a series of monoclonal antibodies, optimized and validated to meet the increasing demands in immunohistochemistry and display the following key features:
Key features include:
– High analytical specificity and sensitivity
– Optimized for high pH hier
– Excellent Stability
– Concentrated Antibodies
– Optimal staining results in external quality assessments
View all our Optibodies™ products here.