New C1s/C1-INH and MASP-1/C1-INH Complex Assays

news September 27 2022

Discover Hycult’s first on the market available ELISA assays to measure early classical and early lectin pathway activation. Tools to investigate, discover and unravel early complement activation in complement-mediated diseases.

Why use C1S/C1-INH Complex Kits?

  • Ready-to-use ELISA’s with a working time of 1 hour and 45 minutes
  • Acute and reliable quantification of C1s/C1-INH complex or MASP-1/C1-INH complex
  • Uses EDTA-plasma as input sample. No need for complement-preserved serum to assess early lectin pathway activation

Why looking at C1-INH and its complexes?

C1-INH administration is an approved common treatment for hereditary angioedema (HAE) and in clinical trials for:

  • Covid-19 infections
  • Prevention of rejection in kidney transplantation
  • Traumatic brain injury and acute ischemic stroke
  • Endotoxemia, sepsis, inflammation and multiple organ failure
  • Application in end stage renal disease and chronic kidney disease

Discover the kit

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