Through our very reputable suppliers, Nordic BioSite offers a comprehensive catalog of outstanding antibodies and reagents for SARS-CoV-2 research. For example the most cited reagent in COVID-19 related papers (in the US) is SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody (GTX632604) from GeneTex, which detects the SARS-CoV-2 spike proteins (S2 subunit).
On the list of most cited Covid-19 Reagents we also find products from ProSci and Sino Biological.
SARS-CoV-2 (COVID-19) Antibodies and Reagents from GeneTex
GeneTex offers a comprehensive catalog of outstanding antibodies and reagents for SARS-CoV-2 research. Antibody clones [HL13402], [HL1014], and [1A9] in particular exhibit high affinity for all SARS-CoV-2 spike proteins, including those of the B.1.1.7 (Alpha), B.1.351 (Beta), and P.1 (Gamma) variants. Recombinant rabbit clone [HL13402], raised against the viral spike S1 subunit, performs exceptionally well when paired with the widely published mouse clone [1A9] (against the S2 subunit) for sandwich ELISA assays. GeneTex’s large collection of spike antibodies virtually guarantees that you will find a reagent appropriate for your desired application. Although there is high homology between different regions of the nucleocapsid proteins from MERS-CoV, SARS-CoV, and SARS-CoV-2, several of GeneTex’s SARS-CoV-2 nucleocapsid antibodies detect only SARS-CoV-2. All recombinant nucleocapsid clones display high affinity for human cell-expressed full-length SARS-CoV-2 nucleocapsid protein, with EC50 values ranging from 0.006-0.074 nM. The SARS-CoV-2 nucleocapsid recombinant antibody pair (GTX635689 and GTX635686) demonstrates superior sensitivity for sandwich ELISA and lateral flow assays. As with the spike antibody catalog, GeneTex’s extensive nucleocapsid antibody listing includes products ideal for all common applications.
SARS-Coronavirus-2 (SARS-CoV-2) Research Reagents from ProSci
ProSci Incorporated offers SARS-CoV-2 antibodies, recombinant proteins, and other reagents related to cellular entry: ACE2 receptor, TMPRSS2, and furin. In addition, ProSci Inc. is continuously adding new SARS-CoV-2 reagents for the spike protein and its sub-regions: S1, S2, the nucleocapsid protein, membrane protein, and envelope protein.
ProSci offers a comprehensive array of SARS-CoV-2 antibodies including llama single-domain antibodies and recombinant proteins, and antibodies against viral proteins; spike, nucleocapsid, envelope, ORF, and NSP. These antibodies can be used for various applications: IHC, Flow Cytometry, ELISA, WB, and Lateral-Flow.
Sino Biological – Reagent Bank for SARS-CoV-2 Research
The recent COVID-19 pandemic caused by SARS-CoV-2 has influenced both the health care systems and economies around the world, and has posed challenges to vaccines, drugs and diagnostics development. Since the outbreak, Sino Biological have been actively tracking the change and movement of the virus to make products “up to date”. Our SARS-CoV-2-related recombinant protein and antibody products have been widely used by researchers across different disciplines and have since generated near 500 citations so far. In addition, those reagents in COVID-19 have been accelerating the progress in serological assay development against SARS-CoV-2. We have also developed the largest bank of recombinant mutant proteins of spike protein, its segments (e.g., S1, RBD, S2), and nucleocapsid. The variant proteins have been actively used by scientists to assess the phenomena of “antibody evasion”caused by the mutagenesis of key residues in the spike protein.